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참여교수 및 연구

  • 참여교수 및 연구
  • 참여교수 개별소개

참여교수 개별소개

이병길, Ph.D.
소속 및 직위
소속: 의예과 , 직위: 조교수
실험실명
분자구조연구실
연구분야
염색체구조형성/단백질생합성/신약개발
연구실위치
암당뇨연구원 S308-1
전공분야
생물리화학/구조생물학

학력 및 경력

2023-, Assistant Professor, Department of Biochemistry, College of Medicine, Gachon University

2017-2023, Investigator Scientist, MRC-LMB, Cambridge, UK

2013-2017, Postdoctoral Fellow, MRC-LMB, Cambridge, UK

2011-2012, Postdoctoral Fellow, Korea University

2011, Ph.D. in Biochemistry, Korea University 

2005, B.S. in Biology, Korea University

 

주요연구업적

- Kim L.*, Lee B.-G.*, Kim M., Kim. M.K., Kwon D.H., Kim H.M., Rho S.-H.#, Song H.K.# (2022) Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis. EMBO J. (2022) 41, e109755. (IF=14.1)

- Lee B.-G.*, Rhodes J.*, Löwe J.# (2022) Clamping of DNA shuts the condensin neck gate. (2022) Proc. Natl. Acad. Sci. USA 119, e21200006119. (IF=12.7)

- Collier J.E.*, Lee B.-G.*, Roig M.B., Yatskevich S., Petela N.J., Metson J., Voulgaris M., Gonzalez Llamazares A., Löwe J.#, Nasmyth K.A.# (2020) Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3. eLife 9, e59560. (IF=8.7)

- Lee B.-G.*, Merkel F.*, Allegretti M., Hassler M., Cawood C., Lecomte L., O'Reilly F.J., Sinn L.R., Gutierrez-Escribano P., Kschonsak M., Bravo S., Nakane T., Rappsilber J., Aragon L.#, Beck M.#, Löwe J.#, Haering C.H.# (2020) Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism. Nat. Struct. Mol. Biol. 27, 743-751. (IF=18.3)

- Lee B.-G.*, Roig M.B., Jansma M., Petela N., Metson J., Nasmyth K.A., Löwe J.# (2016) Crystal structure of the cohesin gatekeeper Pds5 and in complex with Kleisin Scc1. 

Cell Rep. 14, 2108-2115. (IF=9.9)

- Lee B.-G.*, Park E.Y., Lee K.-E., Jeon H., Sung K.H., Paulsen H., Rubsamen-Schaeff H., Brötz-Oesterhelt H., Song H.K.# (2010) Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism. Nat. Struct. Mol. Biol. 17, 371-378. (IF=18.3)