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참여교수 및 연구

  • 참여교수 및 연구
  • 참여교수 개별소개

참여교수 개별소개

강동우, Ph.D.
소속 및 직위
소속: 의예과 , 직위: 부교수
실험실명
나노의학연구실(Nanomedicine Lab)
연구분야
종양학/면역학
연구실위치
암당뇨연구원 N437호
전공분야
암 및 염증치료
  • +82-32-899-6515
  • dkhang@gachon.ac.kr
  • +82-32-833-1525
학력 및 경력

2006 이학박사 (나노의학), Purdue University (West Lafayette)
2010-현재 Associate Editor, International Journal of Nanomedicine (SCI Pharmacology Top 8%)
2014-현재 부교수, 가천대학교 의과대학 의예과 (생리학)

 

 

소개

저희 실험실에서는 인체의 선천 및 획득 면역시스템, 줄기세포가 가진 종양 및 염증 표적 능력, 나노 소포체의 합성 기술을 이용하여 임상 적용이 가능한 난치성 종양 및 염증치료를 위한 차세대 약물을 개발하고 있습니다 

 

키워드

 

면역시스템 조절 항암 약물, 면역 시스템 조절 염증 억제 약물, 줄기세포 단백질을 이용한 표적 소포체의 합성

 


 주요연구실적(교신 저자 기준)


 

1. Unfolded Protein Corona Surrounding Nanotubes Influence the Innate and Adaptive Immune System, Advanced Science (IF=15.8 (cover), 2021) 

2. Mutual Destruction of Deep Lung Tumor Tissues by Nanodrug-Conjugated Stealth Mesenchymal Stem Cells, Advanced Science (IF=15.8 (cover), 2018)

3. Nullifying Tumor Efflux by Prolonged Endolysosome Vesicles: Development of Low Dose Anticancer-Carbon Nanotube Drug, ACS Nano (IF=14.5, 2013)

4. Role of subnano-, nano-and submicron-surface features on osteoblast differentiation of bone marrow mesenchymal stem cells, Biomaterials (IF=10.3, 2012)

5. Destroying Deep Lung Tumor Tissue through Lung-Selective Accumulation and by Activation of Caveolin Uptake Channels Using a Specific Width of Carbon Nanodrug. 

   ACS Applied Materials & Interfaces (IF=8.7, 2018)

6. Control of macrophage responses on hydrophobic and hydrophilic carbon nanostructures. Carbon (IF=8.8, 2011)

7. Triamcinolone-Gold Nanoparticles Repolarize Synoviocytes and Macrophages in Inflamed Synovium. ACS Applied Materials & Interfaces (IF=8.7 (cover), 2020)

8. Apoptotic Lysosomal Proton Sponge Effect in Tumor Tissue by Cationic Gold Nanorods. Nanoscale (IF=6.89, 2019)

9. Analysis on migration and activation of live macrophages on transparent flat and nanostructured titanium, Acta Biomaterialia (IF=6.3, 2011)

10. Arresting cancer proliferation by controlling the surface crystallinity of carbon materials without generating reactive oxygen species, Acta Biomaterialia (IF=6.3, 2012)

11. Triamcinolone–carbon nanotube conjugation inhibits inflammation of human arthritis synovial fibroblasts. Journal of Materials Chemistry B (IF=5.1, 2016)

12. Potential Therapeutic Usage of Nanomedicine for Glaucoma Treatment. International Journal of Nanomedicine (IF=5.1, 2020)

13. Past, Present, and Future of Anticancer Nanomedicine. International Journal of Nanomedicine (IF=5.1, 2020)

14. Mesenchymal stem cell therapy assisted by nanotechnology: a possible combinational treatment for brain tumor and central nerve regeneration. International Journal of Nanomedicine (IF=5.1, 2019)

15. Suppression of human arthritis synovial fibroblasts inflammation using dexamethasone-carbon nanotubes via increasing caveolin-dependent endocytosis and recovering mitochondrial membrane potential. International Journal of Nanomedicine (IF=5.1, 2017)

16. Multiple cues on the physiochemical, mesenchymal, and intracellular trafficking interactions with nanocarriers to maximize tumor target efficiency. International Journal of Nanomedicine (IF=5.1, 2015)

17. High dispersity of carbon nanotubes diminishes immunotoxicity in spleen. 

International Journal of Nanomedicine (IF=5.1, 2015)

18. Effect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity. 

International Journal of Nanomedicine (IF=5.1, 2014)

19. Conformational changes of fibrinogen in dispersed carbon nanotubes. International Journal of Nanomedicine (IF=5.1, 2012)

20. Covalent, Non-Covalent, Encapsulated Nanodrug Regulate the Fate of Intra- and Extracellular Trafficking: Impact on Cancer and Normal Cells. Scientific Reports (IF=4, 2017)