Professor & Research
- Professor & Research
- Research activities(Type)
Research activities(Type)
Research Outline
Study on the anti-inflammatory activity of Smad7
• Generation of transgenic mouse expressing mutant Smad7
• Construction of conditional knockout mouse
• Development of high-throughput screening system for isolating the new drug candidates, activating
expression of Smad proteins
Study on the function of Smad7 as apoptosis sensitizer • Confirmation of activity of Smad7 as anti-tumor agent Study of relationship between TGF-ß and other signaling • Effect of Smad7 on Wnt/ß-catenin signaling
• Effect on the differentiation of Th17 cell and function of IL-17 cytokine
Screening of Smad4 binding elements using ChIP-on-Seq • Finding of new target genes of Smad4-dependent or independent pathway in TGF- signaling
• Understanding of role of Smad4 in biological pathway
Involvement of microRNA in progression or metastasis of tumor • Screening of novel microRNA using parallel sequencing method in gastric cancer models
• Finding new target genes of each microRNA
• Study of role of each microRNA in tumorigenesis
Research Contents
About LAB
Member
- Name Kim, Hyeyoun
- Major
- Email 01199296307@hanmail.net
- Field of Research
- Position
- Name Huyen Trang Ha Thi
- Major
- Email hthtrang@gmail.com
- Field of Research
- Position
- Name Kim, Young Mi
- Major
- Email kim1010@gc.gachon.ac.kr
- Field of Research
- Position