CACU Center of Animal Care and Use
It is the largest and highest animal experiment facility in Korea that can accommodate more than 30,000 rodents with a 3,300 m2 to find mechanism or therapeutic strategy of cancer and diabetes.
It was accredited by AAALAC-I (Association for Assessment and Accreditation of Laboratory Animal Care-International) on June 30, 2020, the second year of its establishment, and has been maintaining full accreditation.
CACU is largely composed of three zones: Animal experiment zone, breeding zone, biosafety level-2 zone and is equipped with in vivo imaging and histopathology laboratory.
And CACU strictly complies with SOP (Standard Operating Procedure) for scientific experiments without
stress, distress, or pain to animals.As a result of these efforts, two tears after the establishment of facility, it was accredited by AAALAC-I.
We would like to make this excellent facility available to domestic and overseas universities, research institutes and pharmaceutical companies to contribute to researches and new drug development in Korea.
Main equipment in CACU
1. In vivo imaging system (IVIS)
Location: Animal experiment zone (A021)
Use and Scope of use
- Utilization for whole body image analysis of animals
- Cancer development and metastasis can be analyzed in a live animal.
- High value in the field of imaging and new drug development
2. Biological X-ray irradiator
Location: Animal experiment zone (A021)
Use and Scope of use
- Use in radiation therapy research with rodents
- X-ray imaging and immunological research can be used
3. Gas anesthesia system
Location: Laboratory rooms in Animal experiment zone
Use and Scope of use
- Gas anesthesia system for rodents
- It can be used for surgery in rodents as rapid induction and recovery of anesthesia
4. Optical and fluorescence microscope (ECLIPS 90i)
Location: General experiment zone (G003)
Use and Scope of use
- Tissue slide assessment
5. Cryosection microtome (Microm HM 520)
Location: General experiment zone (G001)
Use and Scope of use
- Frozen tissue slide production
6. Paraffin section microtome (Microm HM 355)
Location: General experiment zone (G001)
Use and Scope of use
- Paraffin tissue slide production
7. Tissue processing equipment (Shandon Excelsior ES tissue processor)
Location: General experiment zone (G001)
Use and Scope of use
- Tissue process for paraffin block
8. Tissue embedding equipment (Modular tissue embedding center)
Location: General experiment zone (G001)
Use and Scope of use
- Paraffin block production
9. Auto stain equipment (HMS 740)
Location: General experiment zone (G001)
Use and Scope of use
- Hematoxylin and Eosin (H&E) stain for paraffin tissue slide
10. Slide scanner (Mirax)
Location: General experiment zone (G003)
Use and Scope of use
- Tissue slide scanning
11. Micromanipulator (NIKON)
Location: Micromanipulation laboratory (F007)
Use and Scope of use
- Equipment to insert ES cells into the blastocyst while looking at the microscope
- Used for KO (Knock-Out) or Tg (Transgenic) animal production
12. Stereomicroscope (NIKON)
Location: Micromanipulation laboratory (F007)
Use and Scope of use
- Used to collect fertilized eggs or blastocysts from oviduct and uterus of animal
- Used for KO (Knock-Out) or Tg (Transgenic) animal production
13. Micro puller
Location: Micromanipulation laboratory (F007)
Use and Scope of use
- Used to make microtube for micromanipulator
- Used for KO (Knock-Out) or Tg (Transgenic) animal production
14. Micro forge
Location: Micromanipulation laboratory (F007)
Use and Scope of use
- Used to make microtube for micromanipulator
- Used for KO (Knock-Out) or Tg (Transgenic) animal production
15. Micro grinder
Location: Micromanipulation laboratory (F007)
Use and Scope of use
- Used to make microtube for micromanipulator
- Used for KO (Knock-Out) or Tg (Transgenic) animal production
CACU Organization Chart